The Khamsa (Arabic خمسة, literally "five") is an ancient symbol, and serves as a good luck talisman that provides a protecting hand to avert the malevolent and often envious gaze of an "evil eye."

The khamsa comes from folkloric tradition, and is not a part of any religious doctrine. It predates Islam, but is most commonly called the Hand of Fatima after the Prophet Mohammed's daughter. In Jewish culture it is called the Hand of Miriam, after the sister of Moses who saved his life by putting him in a basket by the river.

The Khamsa has, in recent years, become a symbol of the similarities of origins and tradition between the Islamic and Jewish faiths for some activists for Middle East peace.

The symbol is used in amulets, charms, jewelry, door entrances, and other places to ward against the evil eye.